活血补肝肾汤对膝骨性关节炎VAS评分、IL-1β、IL-6和血液黏滞度的影响Effect of Huoxue Bugan decoction on VAS score, IL-1β, IL-6 and blood viscosity with knee osteoarthritis
王星;
摘要(Abstract):
目的观察活血补肝肾汤对膝骨性关节炎患者视觉模拟(VAS)评分、白细胞介素-1β(IL-1β)、IL-6和血液黏滞度的影响。方法选取膝骨性关节炎患者63例,按用药方法随机分为对照组(n=29)和试验组(n=34)。2组患者予以常规西医治疗,试验组患者在此基础上予以活血补肝肾汤口服。结果治疗前2组患者的各项指标比较均无统计学意义(P>0.05)。治疗10周后,试验组的VAS评分、IL-1β、IL-6和血液黏滞度明显低于对照组,2组比较差异均有统计学意义(P<0.05);试验组总有效率为91.2%,对照组总有效率为72.4%,试验组明显高于对照组(P<0.05)。结论活血补肝肾汤治疗膝骨性关节炎能有效改善患者的临床症状及炎症指标。
关键词(KeyWords): 活血补肝肾汤;膝骨性关节炎;白细胞介素;血液黏滞度
基金项目(Foundation): 陕西省中医药管理局计划项目(201679)
作者(Author): 王星;
Email:
DOI: 10.13463/j.cnki.jlzyy.2018.07.015
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