罗利琼;胡林;王继红;霍丹;张小丽;张高;马玉芳;

• 1:武汉科技大学附属天佑医院肿瘤科

摘要(Abstract)：

目的观察加味参麦汤在中晚期食管癌三维适形放疗治疗中的减毒增效作用。方法将63例中晚期食管癌患者随机分为3组,各21例,均采用三维适形放射治疗,放疗对照组(A组)口服配制液,参麦注射液组(B组)予参麦注射液静脉滴注(1次/d),加味参麦汤联合放疗组(C组)同时口服加味参麦汤(50 mL,2次/d),至放疗结束。结果 C组临床获益率高于A组和B组,差异有统计学意义(P<0.05);在生存质量和症状缓解评价方面,C组优于A组和B组(P<0.05);TGF-β1和IL-6在放疗后3组结果无统计学差异(P>0.05)。结论加味参麦汤对中晚期食管癌患者三维适形放疗治疗没有增效的作用;对早期急性放射反应起到一定的减毒作用,但不是通过影响细胞因子TGF-β1和IL-6水平实现的。

关键词(KeyWords)： 加味参麦汤;食管肿瘤;放射疗法;三维适形

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 罗利琼;胡林;王继红;霍丹;张小丽;张高;马玉芳;

Email:

DOI: 10.13463/j.cnki.jlzyy.2014.02.019

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