卓新凤;

• 1:新乡市中医院药剂科

摘要(Abstract)：

目的探讨香丹注射液联合曲美他嗪片对冠心病心绞痛患者疗效及血清炎性因子的影响。方法选取我院收治的78例冠心病心绞痛患者作为研究对象,随机将其分为观察组及对照组,各39例。所有患者均给予硝酸甘油等药物进行常规治疗,对照组另口服给予曲美他嗪片,1片/次,3次/d;观察组在对照组治疗基础上给予香丹注射液(丹参、降香)治疗,1次/d。2组治疗时间均为2周。评价2组综合及心电图疗效。治疗前后,分别检测2组TG、TC、HDL-C及LDL-C等血脂指标,hs-CRP、TNF-α、IL-6及IL-8等炎性因子含量。结果观察组综合及心电图疗效评价中,总有效率分别为84.6%及87.2%,明显高于对照组(P<0.05);治疗后,观察组TG、TC、HDL-C及LDL-C水平分别为(2.27±0.63)mmol/L、(1.43±0.38)mmol/L、(2.12±0.27)mmol/L及(1.69±0.29)mmol/L,改善程度均明显优于对照组(P<0.05);治疗后,观察组hs-CRP、TNF-α、IL-6及IL-8含量分别为(57.4±11.2)ng/m L、(0.84±0.26)pg/m L、(29.6±7.7)ng/m L及(0.29±0.03)ng/m L,均明显低于对照组(P<0.05)。结论香丹注射液联合曲美他嗪片治疗冠心病心绞痛能明显提高治疗效果,改善血脂及炎性因子指标。

关键词(KeyWords)： 香丹注射液;曲美他嗪片;冠心病心绞痛;炎性因子

Abstract:

Keywords:

基金项目(Foundation): 河南省科学技术研究发展计划项目(0424410024)

作者(Author): 卓新凤;

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