张可可;汪悦;

• 1:南京中医药大学第一临床医学院

摘要(Abstract)：

目的探讨麦冬地芍汤治疗干燥综合征的理论依据。方法从中医经典、生理学等方面归纳"肺肠合治法"的科学内涵;分析多篇近年来的国内外文献,总结得出血管活性肠肽与干燥综合征相关。结果宣肺、润肠中药汤剂能够调节模型小鼠肺、肠及颌下腺组织中血管活性肠肽的含量;麦冬地芍汤临床上能有效缓解干燥综合征患者的口干、眼干等症状。结论基于"肺肠合治法"的麦冬地芍汤改善干燥综合征患者的症状可能与上调干燥综合征患者外分泌腺体中血管活性肠肽的表达有关,往后将做进一步的实验研究。

关键词(KeyWords)： 干燥综合征;麦冬地芍汤;肺肠合治法;血管活性肠肽

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金面上项目“基于神经肽VIP研究‘肺肠合治法’治疗干燥综合征的机制”(81473607)

作者(Author): 张可可;汪悦;

Email:

DOI: 10.13463/j.cnki.jlzyy.2016.04.033

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