B型利钠肽与慢性心力衰竭患者中医证型及预后的关系
庞建中;齐新;刘克强;刘玥;
摘要(Abstract)：
目的:研究B型利钠肽(NT-proBNP)水平与慢性心力衰竭(CHF)患者中医证型及其预后的关系。方法:入选CHF患者64例,健康人20例作为对照组。按NYHA分级进行评估,并将患者分为气阴两虚证、气虚血瘀证及心肾阳虚证3种证型。用ELISA染色法测血清NT-proBNP水平。结果:慢性心力衰竭患者3组中医证型组NT-proBNP的水平不同,心肾阳虚证组高于气虚血瘀证和气阴两虚证,差异有统计学意以(P<0.01)。发生终点事件组(心源性死亡,因心功能恶化、急性冠脉综合症、心律失常再入院)NT-proBNP明显高于未发生终点事件组,其中死亡组的NT-proBNP较再入院组升高,各组比较有统计学意义(P<0.01)。结论:血清标记物NT-proBNP对患者的预后具有一定的预测价值,并可作为心力衰竭中医辨证分型的客观化指标之一。
关键词(KeyWords)： 心力衰竭;NYHA分级;B型利钠肽;中医证型
基金项目(Foundation):
作者(Author): 庞建中;齐新;刘克强;刘玥;
Email:
DOI: 10.13463/j.cnki.jlzyy.2012.05.017
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