吕翠岩;刘铜华;

• 1:北京中医药大学

摘要(Abstract)：

糖尿病周围神经病变(DPN)是糖尿病(DM)常见并发病之一,其发病机制主要与血管损害、氧化应激、神经营养因子等因素有关。血管损害包括血管形态结构、功能障碍、活性因子改变和血液流变学异常;氧化应激不仅可以通过活性氧自由基(ROS)介导,刺激细胞内一系列应激信号通路,亦可以直接损伤神经细胞;而神经营养因子的减少则是导致DPN发病的关键因素之一。

关键词(KeyWords)： 糖尿病周围神经病变;发病机制;血管损害;氧化应激;神经营养因子

Abstract:

Keywords:

基金项目(Foundation): 治疗糖尿病周围神经病变药物糖痹康的临床前研究(编号:2012ZX09102-201-001)

作者(Author): 吕翠岩;刘铜华;

Email:

DOI: 10.13463/j.cnki.jlzyy.2012.11.044

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